In the PIVUS study, a cross-sectional analysis revealed that long-chained PFASs, especially PFUnDA, were related to plaque occurrence, but that this association only existed in women. 58 In a longitudinal analysis of the same cohort over 10 years, the change in all of the evaluated PFASs (perfluoroheptanoic acid, PFNA, perfluorodecanoic acid, PFUnDA, PFHxS, PFOS, PFOA, and perfluorooctane
The PIVUS study started in 2001 with the primary aim to investigate the predicive power of different measurements of endothelial function and arterial compliance in a random sample of 1000 subjects aged 70 living in the community of Uppsala. As secondary aims, the study also included measurements of cardiac function and structure by ultrasound and MRI, evaluation of atherosclerosis by
PIVUS (Prospective Investigation of the Vasculature in Uppsala Seniors) Acronym: PIVUS: Description: The PIVUS study started in 2001 with the primary aim to investigate the predicive power of different measurements of endothelial function and arterial compliance in a random sample of 1000 subjects aged 70 living in the community of Uppsala. Persistent organic pollutants and inflammatory markers in a cross-sectional study of elderly swedish people: the PIVUS cohort The PIVUS study started in 2001 with the primary aim to investigate the predicive power of different measurements of endothelial function and arterial compliance in a random sample of 1000 subjects aged 70 living in the community of Uppsala. As secondary aims, the study also included measurements of cardiac function and structure by ultrasound and The PIVUS cohort was used as the discovery cohort. All 70-year-old men and women living in Uppsala, Sweden, between 2001 and 2004 were invited to the PIVUS study (PIVUS-70). 15 In total, 1016 people (507 women and 499 men) took part in the investigation (participation rate=50.1%). These individuals were recruited from the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) cohort.
He is the PI of the ongoing longitudinal cohort study Good Ageing in SKåne (GÅS) part of Swedish National study on Ageing and Care (SNAC) and the cohort study "Men born 1914", and since 2009 coordinating the EpiHealth cohort study in Skåne. Sölves profil i Lunds unviversitets forskningsportal Poly- and perfluoroalkyl substances (PFASs) are a group of man-made fluorinated chemicals which have, at background levels, been associated with negative health effects in humans. 7 Dec 2020 The study sample is a subset of the PIVUS cohort. Elderly participants residing in Uppsala, Sweden were eligible and received an invitation to Uppsala Longitudinal Study of Adult Men cohort (R=20.52 for estimated GFR, R= 0.22 for urinary albumin- tion in the ULSAM and PIVUS cohorts. ACR, eGFR extension assay, and plasma leptin in a cohort of middle-aged patients with T2DM. In the replication cohort PIVUS, only A-FABP (p= 0.0003) but not ADM was The PIVUS study started in 2001 with the primary aim to investigate the predicive 16 Jul 2018 (PIVUS) study were examined with MRI of the brain at age 75 years. Vessel Disease on Neuroimaging in a 75-Year-Old Cohort (PIVUS): 5 Aug 2020 We therefore used data from the PIVUS cohort to evaluate the relationship between POPs and lipids using a longitudinal design.
The mean baseline systolic and diastolic BPs were 144 (19.7)/76 (9.7) mm Hg, and change in systolic and diastolic BPs were 3.7 (15.8)/−0.5 (8.6) mm Hg over 5 years. BACKGROUND: Persistent organic pollutants (POPs) are compounds that are generated through various industrial activities and released in the surrounding environment. 2008-03-19 · By analyzing the data from the same set of 25 SNPs in the ESR1 gene for association with height in the PIVUS cohort, we observed a clear association signal from the SNP rs2179922 located in intron 4 of ESR1 in males from the PIVUS cohort (p = 0.0056) (Table 2).
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The ULSAM cohort (Study I) .. 20 The PIVUS cohort (Study II) ..
in the male samples from the PIVUS cohort. Homozygote carriers of the G-allele of the SNP rs2179922 were on average 0.90 cm taller than individuals with the two other genotypes at this SNP in the ULSAM cohort and 2.3 cm taller in the PIVUS cohort. No association was observed for the females in the PIVUS cohort.
活性( AhR生物活性)和对线粒体功能的影响(ATP浓度)( PIVUS) 23 May 2016 ~1.6% of the genome.
Therefore, we conducted this study utilizing measurements of various circulating POPs in a large population-based sample of men and women aged 70 years from the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) cohort (http://www.medsci.uu.se/pivus/). PIVUS - Prospective Investigation of the Vasculature in Uppsala Seniors This study is part of the collection Swedish Cohort Consortium (Cohorts.se), Swedish Diet Cohort Consortium (SDCC) Overview Description Data and documentation Published: 2015-04-19
Assessment of potential confounders of the association between urobilin and sphingomyelin (30:1), and incident heart failure, respectively, in the PIVUS cohort (n = 829, number of events = 58). Table S5. Association of each urobilin metabolite in ULSAM, PIVUS and TwinGene combined – age and sex adjusted. Table S6.
Results: During follow-up, 413 participants died in the ULSAM cohort (incidence rate: 3.59/100 person-years at risk) and 100 participants died in the PIVUS cohort (incidence rate: 1.32/100 person-years at risk). In multivariable Cox regression models adjusted for age, systolic blood pressure, diabetes, smoking status, body mass index, total
These individuals were recruited from the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) cohort.
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We used a total toxic equivalency (TEQ) value that measures toxicological effects with the relative potencies of various POPs. The longitudinal change in concentration of eight PFASs detected in serum collected from the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) cohort were determined and compared to results from general population studies. The sex-dependent changes in PFAS concentrations over time were also assessed. Therefore, we conducted this study utilizing measurements of various circulating POPs in a large population-based sample of men and women aged 70 years from the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) cohort (http://www.medsci.uu.se/pivus/).
Methods Study population We used data that had been generated previously
the Vasculature in Uppsala Seniors (PIVUS) cohort study. All individuals who were 70 years of age and liv-ing in Uppsala, Sweden, were invited.
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Uppsala Seniors (PIVUS; women 50%, n=1005, mean age 70 years, median follow-up 7.9 years) and the Uppsala Longitudinal Study of Adult Men (ULSAM, n=775, mean age 77 years, median follow-up 8.1 years). Results: In total, 101 participants in PIVUS and 274 in ULSAM died during
15 In total, 1016 people (507 women and 499 men) took part in the investigation (participation rate=50.1%).